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Continue reading →: 2023: The year of resilience
by Inam Makhabana This year started on a positive note for me, I was highly motivated and thrilled to begin my postgraduate studies, not thinking much into what to expect and how my experience of transitioning from undergraduate to postgraduate would feel like, all that was in my mind was…
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Continue reading →: What drives The Resistance of the TGF-beta pathway to CRISPR Cancer Therapy?
by Phahlamohlaka Mokgohlwer Cynthia Due to numerous limitations that come with the study and clinical application of the genetic engineering technique CRISPR on tumor cells. This research addresses some of the important and crucial factors, accuracy, and robustness cautiously on cancer therapy. Incorrect genetic editing and modification in the medical…
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Continue reading →: CRISPR-Cas9 Editing of the HBG1 and HBG2 Promoters to Treat Sickle Cell Disease
by Gemma Gauntlett Background Pre-birth, individuals have fetal hemoglobin (α2 γ 2), which consists of 2 alpha-globin (α2) subunits and 2 gamma-globin (γ2) subunits. Around the time of birth, y-globin gene (HBG1 and HBG2) production switches to B-globin (HBB), causing the level of fetal hemoglobin (α2 γ2) to decrease and…
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Continue reading →: A little scientist
by Paige Mackenzie At the start of the new year, I knew very little about what doing an honours meant. As an undergrad we read a lot of papers, looked at a lot of graphs and memorised a lot of things. Now as much as I found that interesting –…
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